eCysticFibrosis Review
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VOLUME 6 - ISSUE 2

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POST TEST

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The Current State of CFTR Modification

 

Our guest author is Noah Lechtzin, MD from the Johns Hopkins University in Baltimore, Maryland.

After participating in this activity, the participant will demonstrate the ability to:

  • Explain the long-term benefits of ivacaftor therapy in people with G551D CFTR mutations.
  • Describe the effects of ivacaftor therapy in people with non-G551D CFTR mutations.
  • Evaluate the impact of the combination of ivacaftor plus lumacaftor in people with two F508del CFTR mutations.
  • Describe the current research into therapeutic options for people with CFTR class I also known as nonsense or missense mutations.
  • This discussion, offered as a downloadable audio file and companion transcript, covers the important issues related to the current state of CFTR-modifying therapies in the format of case-study scenarios for the clinical practice. This program is a follow up to Volume 6, Issue 1 eCysticFibrosis Review Newsletter - The Current State of CFTR Modifier Therapy.

    Unlabeled/Unapproved Uses
    Dr. Lechtzin has disclosed that his discussion today will refer to certain off-label or unapproved uses of lumacaftor, ivacaftor, and ataluren.

     

    MEET THE AUTHOR

     

     

    lechtzin, md

    Noah Lechtzin, MD
    Director, Adult Cystic Fibrosis Program
    Associate Professor of Medicine
    Johns Hopkins University
    Baltimore, Maryland

     

     

     

     

    Guest Faculty Disclosure
    Dr. Noah Lechtzin has reported that he has served as principal investigator for Vertex Pharmaceuticals Incorporated. In addition, he has served as a consultant for Hill Rom.


    Release Date: Expiration Date:
    January 28, 2016 January 27, 2018

     

     

     

     

    OTHER RESOURCES

     

     

     

    Download the podcast transcript

    Go to the companion newsletter

     

     

     

     


    PROGRAM DIRECTORS

    Peter J. Mogayzel, Jr., MD, PhD
    Professor of Pediatrics
    Director, Cystic Fibrosis Center
    Johns Hopkins University
    Baltimore, MD

    Noah Lechtzin, MD
    Director, Adult Cystic Fibrosis Program
    Associate Professor of Medicine
    Johns Hopkins University
    Baltimore, MD

     

     

    Suzanne Sullivan, RN, BSN
    Senior Clinical Nurse
    Johns Hopkins Hospital
    Baltimore, MD

     

     

     

     

    CME/CE INFORMATION

     

     

    ACCREDITATION STATEMENT

    Physicians
    This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Johns Hopkins University School of Medicine and The Institute for Johns Hopkins Nursing. The Johns Hopkins University School of Medicine is accredited by the ACCME to provide continuing medical education for physicians.

    Nurses
    The Institute for Johns Hopkins Nursing is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation.

    CREDIT DESIGNATION STATEMENT

    Physicians
    Podcast: The Johns Hopkins University School of Medicine designates this enduring material for a maximum of 0.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Nurses
    Podcast: This 0.5 contact hour Educational Activity is provided by the Institute for Johns Hopkins Nursing. Each Podcast carries a maximum of 0.5 contact hour, or a total of 3 contact hours for the 6 podcasts in this program.

     

    INTERNET CME POLICY

    DISCLAIMER STATEMENT

    STATEMENT OF RESPONSIBILITY

    STATEMENT OF NEED
    INTENDED AUDIENCE

    CONFIDENTIALITY DISCLAIMER FOR CME ACTIVITY PARTICIPANTS

    HARDWARE & SOFTWARE REQUIREMENTS

    COMPLETE CME INFORMATION

     


    All rights reserved - The Johns Hopkins University School of Medicine.

    This activity was developed in collaboration with DKBmed.